PT-141, also known as Bremelanotide, is a modified cyclic peptide supplied for controlled laboratory, analytical, and scientific research.
Its structure contains an N-terminal acetyl group, norleucine, a D-phenylalanine residue, and an intramolecular cyclic linkage. These structural features distinguish PT-141 from a conventional linear peptide and should be preserved in technical documentation.
The commonly referenced free peptide is associated with CAS 189691-06-3, molecular formula C₅₀H₆₈N₁₄O₁₀, and molecular weight approximately 1025.2 g/mol.
Research Applications
PT-141 may be examined in controlled non-clinical research involving:
- Modified peptide characterization
- Ligand-receptor interaction studies
- Molecular signaling research
- Structure-function analysis
- Cyclic peptide characterization
- Stereochemistry-focused studies
- Analytical comparison
- Non-clinical biochemical models
Any experimental observations should remain specific to the applicable research system and should not be interpreted as evidence of behavioral, reproductive, therapeutic, or clinical effectiveness.
Structural Information
PT-141 is commonly represented as:
Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-OH
Important structural characteristics include:
- N-terminal acetylation
- Norleucine residue
- D-phenylalanine residue
- Cyclic peptide architecture
- Seven amino-acid-derived residues
Because stereochemistry and cyclization are part of its identity, a simplified one-letter sequence alone is not sufficient for complete structural documentation.
Salt-Form Considerations
PT-141 may also be supplied in acetate-associated forms.
A reported acetate form has different molecular specifications from the free peptide. Therefore:
- Free-base and acetate values should not be used interchangeably
- Counter-ion status should be confirmed
- Molecular formula and molecular weight should match the applicable COA
Analytical Identification
Relevant analytical characterization may include:
- Peptide identity confirmation
- Molecular mass assessment
- Stereochemical verification
- Cyclic-structure confirmation
- Counter-ion analysis
- Chromatographic purity testing
- Lot-specific analytical assessment
Specifications & Documentation
Lot-specific documentation should be reviewed for:
- Product identity
- CAS number
- Molecular formula
- Molecular weight
- Peptide sequence
- Structural modifications
- Salt or counter-ion form
- Purity specification
- Analytical methodology
- Lot or batch information
- Certificate of Analysis
- Storage requirements
Authenticated lot-specific analytical documentation should take precedence over generalized reference values.
Storage & Handling
Store according to conditions specified on the product label and Certificate of Analysis. Protect the material from environmental conditions that may compromise peptide integrity.
Handling should follow established laboratory procedures appropriate for research materials.
Research Use Only
PT-141 is supplied exclusively for laboratory research, analytical testing, and scientific reference purposes.
Disclaimer
For research use only. Not for human or veterinary use. Not intended for consumption, administration, sexual or reproductive use, diagnosis, treatment, mitigation, cure, or prevention of any disease. No therapeutic, behavioral, reproductive, medical, or clinical claims are made or implied. Product information is supplied solely for scientific identification, documentation, and research reference.
