MGF, commonly referred to as Mechano Growth Factor, is a synthetic peptide corresponding to a C-terminal E-domain sequence associated with the IGF-1Ec splice variant.
Commercial research materials sold as MGF are generally based on a 24-residue peptide sequence. However, published and supplier sources show inconsistencies in terminal residues, molecular formula, calculated molecular mass, and CAS assignments.
A commonly marketed synthetic research sequence is:
YQPPSTNKNTKSQRRKGSTFEEHK
with a reported molecular mass of approximately 2.85-2.87 kDa. Current supplier references are not fully consistent on the exact CAS number or molecular formula.
Research Applications
MGF may be examined in controlled non-clinical research involving:
- Peptide identity and characterization
- IGF-related splice-variant research
- Molecular interaction studies
- Structure-function analysis
- Analytical peptide comparison
- Stability assessment
- Non-clinical biochemical and cellular models
Any findings should remain specific to the applicable research model and should not be interpreted as evidence of muscle-building, recovery, performance enhancement, therapeutic effectiveness, or suitability for human use.
Structural Information
A commonly referenced MGF research sequence is:
Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys
One-letter representation:
YQPPSTNKNTKSQRRKGSTFEEHK
Some references instead report terminal sequence variants such as …FEERK, creating small differences in molecular formula and calculated molecular weight. This is why the exact client COA should be treated as the controlling specification.
Analytical Identification
Relevant analytical characterization may include:
- Amino-acid sequence confirmation
- Molecular mass assessment
- Terminal-residue verification
- Chromatographic purity testing
- Peptide identity confirmation
- Structural characterization
- Lot-specific quality analysis
Specifications & Documentation
Lot-specific documentation should be reviewed for:
- Exact peptide sequence
- Molecular formula
- Molecular weight
- CAS identifier, if assigned
- Terminal structure
- Salt or counter-ion form
- Purity specification
- Analytical testing
- Lot or batch information
- Certificate of Analysis
- Storage requirements
Authenticated lot-specific analytical documentation should take precedence over generalized supplier records.
Storage & Handling
Store according to the conditions specified on the product label and Certificate of Analysis. Protect the material from environmental conditions that could compromise peptide integrity.
Handling should follow established laboratory procedures appropriate for research materials.
Research Use Only
MGF is supplied exclusively for laboratory research, analytical testing, and scientific reference purposes.
Disclaimer
For research use only. Not for human or veterinary use. Not intended for consumption, administration, muscle-building use, recovery-related use, performance enhancement, diagnosis, treatment, mitigation, cure, or prevention of any disease. No therapeutic, anabolic, recovery-related, performance-related, medical, or clinical claims are made or implied. Product information is supplied solely for scientific identification, documentation, and research reference.




