SS-31

SS-31

Price range: $148.48 through $219.00

Full Name: Elamipretide
Alternative Names: MTP-131, Bendavia
CAS #: 736992-21-5
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight (M.W.): Approximately 639.8 g/mol
Sequence: D-Arg-Dmt-Lys-Phe-NH₂
Sequence Representation: RXKF
Length: 4 residues
Product Type: Modified Synthetic Tetrapeptide

SS-31, also known as Elamipretide or MTP-131, is a structurally modified tetrapeptide supplied for controlled laboratory, analytical, and scientific research.

PubChem lists Elamipretide with CAS 736992-21-5, molecular formula C₃₂H₄₉N₉O₅, and molecular weight approximately 639.8 g/mol. Its condensed structure is represented as H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH₂, where the modified tyrosine residue is commonly referred to as Dmt (2,6-dimethyltyrosine).

Because SS-31 contains a D-amino-acid residue, a non-standard modified tyrosine residue, and C-terminal amidation, its complete identity should not be represented by a conventional one-letter sequence alone.

Research Applications

SS-31 may be examined in controlled non-clinical research involving:

  • Modified peptide characterization
  • Peptide-lipid interaction studies
  • Molecular binding research
  • Structure-function analysis
  • Mitochondrial membrane research models
  • Analytical peptide comparison
  • Stability studies
  • Non-clinical biochemical and cellular systems

Any experimental observations should remain limited to the relevant model and should not be interpreted as evidence of therapeutic effectiveness or suitability for human or veterinary use.

Structural Information

SS-31 is commonly represented as:

H-D-Arg-Dmt-Lys-Phe-NH₂

where:

  • D-Arg = D-arginine
  • Dmt = 2,6-dimethyltyrosine
  • Lys = lysine
  • Phe-NH₂ = C-terminal phenylalaninamide

PubChem uses the abbreviated sequence representation RXKF, with the modified residue encoded separately in its structural record.

Salt-Form Considerations

SS-31 may also be supplied in salt forms with different molecular specifications.

For example, PubChem lists Elamipretide TFA with:

  • CAS #: 1606994-55-1
  • Molecular Formula: C₃₄H₅₀F₃N₉O₇
  • Molecular Weight: Approximately 753.8 g/mol

Elamipretide hydrochloride is another distinct form with separate molecular specifications.

The exact product form should therefore be confirmed against the lot-specific Certificate of Analysis.

Analytical Identification

Relevant analytical characterization may include:

  • Peptide identity confirmation
  • Molecular mass assessment
  • Modified-residue verification
  • Stereochemical confirmation
  • C-terminal amidation verification
  • Counter-ion identification
  • Chromatographic purity testing
  • Lot-specific quality analysis

Specifications & Documentation

Lot-specific documentation should be reviewed for:

  • Product identity
  • CAS number
  • Peptide sequence
  • Modified residue identity
  • Molecular formula
  • Molecular weight
  • Salt or counter-ion form
  • Purity specification
  • Analytical testing
  • Lot or batch information
  • Certificate of Analysis
  • Storage requirements

Authenticated lot-specific analytical records should take precedence over generalized reference data.

Storage & Handling

Store according to conditions specified on the product label and Certificate of Analysis. Protect the material from environmental conditions that may compromise peptide integrity.

Handling should follow established laboratory procedures appropriate for research materials.

Research Use Only

SS-31 is supplied exclusively for laboratory research, analytical testing, and scientific reference purposes.

Disclaimer

For research use only. Not for human or veterinary use. Not intended for consumption, administration, diagnosis, treatment, mitigation, cure, or prevention of any disease. No therapeutic, mitochondrial, performance-related, medical, or clinical claims are made or implied. Product information is supplied solely for scientific identification, documentation, and research reference.

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