MT-2, also known as Melanotan II, is a synthetic cyclic seven-residue peptide supplied for controlled laboratory, analytical, and scientific research.
Its molecular structure includes N-terminal acetylation, norleucine, D-phenylalanine, C-terminal amidation, and an intramolecular cyclic linkage. These structural features distinguish MT-2 from linear MT-1.
PubChem lists Melanotan II with CAS 121062-08-6, molecular formula C₅₀H₆₉N₁₅O₉, molecular weight approximately 1024.2 g/mol, and condensed sequence Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH₂.
Research Applications
MT-2 may be examined in controlled non-clinical research involving:
- Cyclic peptide characterization
- Ligand-receptor interaction studies
- Molecular signaling research
- Structure-function analysis
- Analytical peptide comparison
- Conformational studies
- Stability assessment
- Non-clinical biochemical and cellular models
Experimental observations should remain limited to the applicable research system and should not be interpreted as evidence of cosmetic, pigmentation-related, behavioral, therapeutic, or clinical effectiveness.
Structural Information
MT-2 is represented as:
Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH₂
Key structural features include:
- N-terminal acetylation
- Norleucine residue
- D-phenylalanine
- Cyclic peptide linkage
- C-terminal amidation
MT-2 is therefore chemically and structurally distinct from MT-1.
Analytical Identification
Relevant characterization may include:
- Peptide identity confirmation
- Sequence verification
- Cyclic linkage confirmation
- Modified-residue verification
- Molecular mass assessment
- Chromatographic purity testing
- Structural analysis
- Lot-specific quality testing
Specifications & Documentation
Lot-specific documentation should be reviewed for:
- Compound identity
- Peptide sequence
- Molecular formula
- Molecular weight
- Cyclization state
- Salt or counter-ion form
- Purity specification
- Analytical testing
- Lot or batch information
- Certificate of Analysis
- Storage requirements
Authenticated lot-specific documentation should take precedence over generalized reference values.
Storage & Handling
Store according to the conditions specified on the product label and Certificate of Analysis. Protect the material from environmental conditions that could compromise peptide integrity.
Handling should follow established laboratory procedures appropriate for research materials.
Research Use Only
MT-2 is supplied exclusively for laboratory research, analytical testing, and scientific reference purposes.
Disclaimer
For research use only. Not for human or veterinary use. Not intended for consumption, administration, cosmetic use, pigmentation-related use, behavioral use, diagnosis, treatment, mitigation, cure, or prevention of any disease. No therapeutic, cosmetic, behavioral, dermatological, medical, or clinical claims are made or implied. Product information is supplied solely for scientific identification, documentation, and research reference.




